SCIENCE OF RNAi
Therapeutic Potential
RNAi science was originally discovered in 1998 by Andrew Fire and Craig Mello and resulted in a Nobel Prize for the two men.
Over the last decade, researchers have learned that, by introducing siRNA into a cell they can selectively direct the body’s natural RNAi process to suppress the undesirable product of a “disease” gene. RNAi is a fundamentally different approach to disease management as compared to more traditional or current therapeutic modalities involving small molecules and biologics.
With the molecular causes of numerous diseases now being more clearly defined, many believe that RNAi offers significant therapeutic potential. This includes the potential to treat any disease in which there is a target gene identified including disease targets that are currently considered “undruggable” by conventional small molecules or antibodies.
RNAi Opportunities
